Phenol, 2,3,4-trimethoxy-
2,3,4-Trimethoxyphenol
CAS: 19676-64-3
Molecular Formula: C9H12O4
Phenol, 2,3,4-trimethoxy- - Names and Identifiers
| Name | 2,3,4-Trimethoxyphenol |
| Synonyms | 2,3,4-Trimethoxyphen 2,3,4-Trimethoxyphenol 2,3,4-TRIMETHOXYPHENOL 2,3,4-Trimethoxybenzolol Phenol, 2,3,4-triMethoxy- Phenol, 2,3,4-trimethoxy- |
| CAS | 19676-64-3 |
| InChI | InChI=1/C9H12O4/c1-11-7-5-4-6(10)8(12-2)9(7)13-3/h4-5,10H,1-3H3 |
Phenol, 2,3,4-trimethoxy- - Physico-chemical Properties
| Molecular Formula | C9H12O4 |
| Molar Mass | 184.19 |
| Density | 1.152±0.06 g/cm3(Predicted) |
| Melting Point | 44.5 °C |
| Boling Point | 150-155 °C(Press: 2.5 Torr) |
| Flash Point | 128.7°C |
| Vapor Presure | 0.00129mmHg at 25°C |
| pKa | 10.10±0.23(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.514 |
Phenol, 2,3,4-trimethoxy- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
Phenol, 2,3,4-trimethoxy- - Introduction
2,3,4-Trimethoxyphenol is an organic compound with the formula C10H14O3. The following is a description of its nature, use, preparation and safety information:
Nature:
2,3,4-Trimethoxyphenol is a solid with a white or off-white crystalline form. Its melting point is 156-158 degrees Celsius. The compound is sparingly soluble in water and soluble in organic solvents such as ethanol, acetone and dichloromethane.
Use:
2,3,4-Trimethoxyphenol is widely used in chemical and pharmaceutical fields. It can be used as an intermediate in the synthesis of drugs, such as the anticancer drug Glecaprevir. In addition, it can also be used as an additive for rubber antioxidants, coatings and adhesives.
Method:
2,3,4-Trimethoxyphenol can be synthesized by esterification of p-Cresol (p-methylphenol) and methanol under appropriate conditions. The specific steps are: heating and reacting Cresol with methanol, and after esterification, 2,3,4-Trimethoxyphenol is obtained.
Safety Information:
2,3,4-Trimethoxyphenol has lower toxicity, but still has certain safety risks. During the operation, direct contact with skin and eyes should be avoided, and good ventilation conditions should be maintained. If contact occurs, rinse immediately with plenty of water and seek medical help. When stored, it should be placed in a sealed container, away from fire and oxidizing agents. If waste is to be disposed of, it should be disposed of in accordance with local regulations. In the process of use, please abide by the relevant safety operation procedures.
Nature:
2,3,4-Trimethoxyphenol is a solid with a white or off-white crystalline form. Its melting point is 156-158 degrees Celsius. The compound is sparingly soluble in water and soluble in organic solvents such as ethanol, acetone and dichloromethane.
Use:
2,3,4-Trimethoxyphenol is widely used in chemical and pharmaceutical fields. It can be used as an intermediate in the synthesis of drugs, such as the anticancer drug Glecaprevir. In addition, it can also be used as an additive for rubber antioxidants, coatings and adhesives.
Method:
2,3,4-Trimethoxyphenol can be synthesized by esterification of p-Cresol (p-methylphenol) and methanol under appropriate conditions. The specific steps are: heating and reacting Cresol with methanol, and after esterification, 2,3,4-Trimethoxyphenol is obtained.
Safety Information:
2,3,4-Trimethoxyphenol has lower toxicity, but still has certain safety risks. During the operation, direct contact with skin and eyes should be avoided, and good ventilation conditions should be maintained. If contact occurs, rinse immediately with plenty of water and seek medical help. When stored, it should be placed in a sealed container, away from fire and oxidizing agents. If waste is to be disposed of, it should be disposed of in accordance with local regulations. In the process of use, please abide by the relevant safety operation procedures.
Last Update：2024-04-09 20:52:54
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Email: r@reformchem.com
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Product Name: 2,3,4-Trimethoxyphenol Visit Supplier Webpage Request for quotationCAS: 19676-64-3
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